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Post graduate research scholarship
Department of Medicine and Centre for Magnetic Resonance
Topic: This is an interdisciplinary project between the Department of
Medicine and the Centre for Magnetic Resonance. The goal of this project
is the evaluation of an animal model of multiple sclerosis with magnetic
resonance imaging and spectroscopy techniques.
Nuclear magnetic resonance (NMR) is a relatively new technique that has
become an indispensable tool for the noninvasive investigation of
disease within the nervous system. NMR permits the visualization of
anatomical structures, such as the rat spinal cord, the determination of
the concentration of some biochemically relevant compounds, and the
investigation of some physiological characteristics of the sample such
as flow through blood vessels and the diffusion of free water through
the region of interest. Anatomical images are produced by placing
objects of interest, such as the brain, in a strong magnetic field
created by a superconducting magnet. The generation of a signal by the
object is accomplished by firstly inducing brief changes in the main
magnetic field with a small resonating coil placed near the object. These
brief changes in the main magnetic field, created by the electric
current within the resonating coil, briefly alter the plane of spinning
of the protons within the stronger, main magnetic field created by the
superconducting magnet. Whilst the protons are spinning in the newer
plane, they produce a high frequency magnetic field that can induce
currents in a nearby second surface coil. The currents induced in the
nearby surface coil are used to derive information, that is processed by
a computer, about the composition and structure of the object. This data
obtained reflects the concentration of various substances within the
object of interest. Images, derived from magnetic resonance studies,
are based upon at least three kinds of contrast that reflect differences
in tissue biochemistry. The orientation of the images are under
operator control and can be precisely oriented to internal brain and
spinal cord landmarks. This feature accounts for a significant improvement
in the visualization of structures (100 microns or less) Magnetic
resonance imaging (MRI) and in vivo magnetic resonance spectroscopy
(MRS) pulse sequences can be chosen to clearly delineate the structural
detail of the tissue of interest, provide biochemical data or study some
other feature such as blood flow, oedema or blood-brain barrier
breakdown.
Applicants who hold or expect to obtain an honours degree (preferably
first class) or an equivalent qualification in medicine, physics,
chemistry, radiography or biological sciences are invited to apply for a
postgraduate research scholarship in the use of magnetic resonance
imaging and spectroscopy in an animal model of multiple sclerosis.
The long range goal of this project is to accurately age the inflammatory
demyelinating lesions of mutliple sclerosis.
Scholarship value: $15,364 per annum. For a medical graduate, a
scholarship of $27,364 is offerred. Additional part time work may be
available.
For further information contact: Dr. Jonathan Chalk on telephone
07-33654100, fax 61-7-33654240 or j.chalk@cmr.uq.edu.au
Applications should be made to
The Director
Centre for Magnetic Resonance
The University of Queensland
Brisbane 4072.
Closing date for applications: April 15, 1996.
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Post graduate research scholarship
Department of Medicine and Centre for Magnetic Resonance
Topic: This is an interdisciplinary project between the Department of
Medicine and the Centre for Magnetic Resonance. The goal of this project
is the evaluation of an animal model of multiple sclero
Nuclear magnetic resonance (NMR) is a relatively new technique that has
become an indispensable tool for the noninvasive investigation of disease
within the nervous system. NMR permits the visualiza
Applicants who hold or expect to obtain an honours degree (preferably
first class) or an equivalent qualification in medicine, physics,
chemistry, radiography or biological sciences are invited to a
The long range goal of this project is to accurately age the inflammatory
demyelinating lesions of mutliple sclerosis.
Scholarship value: $15,364 per annum. For a medical graduate, a
scholarship of $27,364 is offerred. Additional part time work may be
available.
For further information contact: Dr. Jonathan Chalk on telephone
07-33654100, fax 61-7-33654240 or j.chalk@cmr.uq.edu.au
Applications should be made to
The Director
Centre for Magnetic Resonance
The University of Queensland
Brisbane 4072.
Closing date for applications: April 15, 1996.
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Wolfgang U. Roffmann |Phone: +61 7 3365 4453 R&D
Eng/Operations Manager |Fax:+61 7 3365 3833
Centre for Magnetic Resonance |Email:wolfgang@cmr.uq.edu.au The
University of Queensland |URL http://www.uq.edu.au/cmr/cmr.html
St.Lucia, Qld, 4072
Australia
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"The way to get things done is not to worry who gets the credit for it"