ROESY/TROESY and TOCSY problems
Charles Anderson PD|GWK (ANDERSON@novell.chem.utk.edu)
Mon, 28 Oct 1996 09:32:30 EST
I have been working with a small molecule complex (MW about 400)
on an AMX-400 running a ROESY pulse sequence and have had some
success picking up the NOE interaction. I have also calculated the
desired internuclear distances. However, I am having some problem
with TOCSY breakthrough which litters the spectrum a little. I have
switched to a TROESY pulse sequence to rid myself of this problem,
but it still occurs. How can I rid myself of this annoying little
problem? I know it is possible because I have seen clean spectra in
the lit.
My second question is may I use the TROESY to calculate the
internuclear distances in the same manner as the ROESY?
Charles L. Anderson, Ph.D.
Department of Chemistry
University of Tennessee
Knoxville, TN 37996-1600
Telephone:(423)974-3473 or 974-3661