> Dear Spinlanders,
>
> Would like to here from anyone who has done 1H NMR on 3H labelled compounds
> and{or} 13C NMR on 14C labelled compounds. Trying to get information
> concerning appropriate precautions and safe handling techniques for hot atom
> NMR. Also, trying to determine if an NRC license is required for solvated
> samples with following maximum activities:
>
> 3H, 1 milli Curie
> 14C, 100 micro Curies
>
Dear Lawrence,
Regarding 3H NMR, a good source of information is the web page
of the National Tritium Labeling Facility at the Lawrence Berkeley
Laboratory (http://www.lbl.gov/LBL-Programs/NTLF/).
This will direct you to many more recent references on 3H NMR. In
particular the following reference gives some good sample handing
info : "Applications of High Resolution 3H NMR Spectroscopy", P.G.
Williams, Fusion Technol., 14, 840-844 (1988).
hope this helps,
Tom O'C.
****************************************************
Thomas M. O'Connell
Assistant Professor of Medicinal Chemistry
School of Pharmacy, CB #7360
University of North Carolina
Chapel Hill, NC 27599-7360