NMR Position

Renato Toffanin (toffanin@pcnmr1.univ.trieste.it)
Thu, 13 Aug 1998 16:29:51 +0200 (MET DST)

NMR SCIENTIST - POSITION OPEN

Orion Corporation
ORION PHARMA
Preclinical Research
P.O.box 65 FIN-02101 Espoo
Finland

The Orion Group is the leading company in the Finnish health care sector.
The pharmaceutical division, Orion Pharma, is seeking a substantial role in
pharmaceuticals in Europe. This aim is pursued by developing competitive
products through in-house R & D for specific areas, and by strengthening
and expanding the present market position. Our future success will be driven
by highly competent and committed scientists and specialists working together
in teams.

In the Structural Chemistry Laboratory of the Preclinical Research a
position is open for a research scientist specialized in NMR spectroscopy

A qualified candidate has a Ph.D. and research experience in liquid NMR,
with documented skills in multidimensional heteronuclear NMR spectroscopy,
preferably with experience in protein structure determination and
screening methodologies. A background in biochemistry, or molecular
biology is desirable, as well the familiarity with software such as InsightII
and FELIX (Molecular Simulations) and with UNIX/SGI in general. An
excellent interpersonal and networking skills and fluency in English are also
required.

The successful candidate will work on two Bruker NMR spectrometers (AC300,
ARX400 MHz with z-gradient) located at the Orion Research Center in Espoo
(Helsinki metropolitan area) and will cooperate with a team of research
scientists involved in the drug discovery process. He/she will be
responsable for studies on the fine structure of products, the structure of
peptides and proteins, the drug target-ligand interactions and binding
characterization. He/she will eventually perform also metabolic studies
on isolated perfused organs and detection and quantification of metabolites
and xenobiotics in biological fluids or extracts. Moreover, he/she will take
part in research cooperation with academic groups studying protein and
protein-ligand structures with higher field spectrometers.

Salary level will be commensurate with qualifications and experience.
Applicants should submit a curriculum vitae, including list of
publications and a description of their present research activity, to Dr.
Martti Ovaska, Orion Pharma, Preclinical Research, P.O.box 65, FIN-02101 Espoo,
Finland before September, 6, 1998. For further information, contact Dr.Martti
Ovaska, Manager of the Structural Chemistry Laboratory, at int-358-9-429-2536
(e-mail: martti.ovaska@orion.mailnet.fi) or Dr.Piero Pollesello, Head of
Cardiovascular Preclinical Research, at int-358-9-429-4191 (e-mail: piero.
pollesello@orion.mailnet.fi), FAX:int-358-9-429-2924.