I've been asked if it is possible to obtain a spectrum of a sample
with an impurity that is roughly 1000 times more concentrated. The
person is looking at some electrolysis products in the presence of
supporting electrolyte. I would like to either eliminate the signal
from the supporting electrolyte, or set up an experiment where I can
still get reasonable resolution on the sample. I'm just concerned with
1H-NMR and (at least for the current samples) the signal we are
interested in is >7ppm while the supporting electrolyte has three
features all <4ppm. The two ideas I have are:
1.) some sort of presaturation method which would ultimately eliminate
any signal within the 1-4(5) ppm range...I am aware that this is
probably not the best option
2.) use some sort of processing that will allow me to improve the sample
signal. What I was thinking is to increase the receiver gain so I could
detect the sample's signal, but would undoubtedly be too high for the
supporting electrolyte. However if I were to do some sort of window
function (gaussian multiplication?) which would recreate the part of the
FID that gets cut off by the high receiver gain, I thought I might be
able to solve my problem.
Any ideas? Sorry for the long-winded post.
BoB
--
To most people solutions mean finding the answers. But to
chemists solutions are things that are still all mixed up.
-unknown