McMaster University - Chem2O06 1997/98

Chemistry 2O06: Organic Chemistry

Chemistry 2O06 is an introductory course in organic chemistry for scientists not majoring in chemistry. Emphasis is placed on the structure of organic compounds and on the reactivity associated with functional groups.


[Chapter & Section references are to Organic chemistry; S. Ege Organic Chemistry, Heath, 3rd Edition]


[Chapter 1 - Week 1]
Brief Review of some topics discussed in Chem. 1A06: bonding, Lewis structures, resonance, bond polarity, molecular & structural formulae, intermolecular forces

[Chapter 2 - Week 2]
Molecular orbitals, hybridization, structural isomers, functional groups

[Chapter 3 - Week 3]
Organic acids and bases

[Chapter 4 - Week 4]
Reaction Mechanisms: electrophiles and nucleophiles, nucleophilic substitution, electrophilic addition, rates of chemical reactions

[Chapter 5 - Week 5]
Alkanes & cycloalkanes, nomenclature, conformers & rotamers, chemical properties

[Chapter 6 - Week 6-7]
Stereochemistry: chirality, absolute configuration, enantiomers & diastereomers, halogen addition to alkenes, stereoisomerism in cycloalkanes and alkanes, resolution of enantiomers

[Chapter 7 - Week 7-8]
Nucleophilic substitution and elimination reactions

[Chapter 8 - Week 9]
Alkenes: structure, nomenclature, preparation, reactions

[Chapter 9 - Week 10]

[Chapter 10 - Week 10-11]
Infrared Spectroscopy

[Chapter 11 - Week -11-12]
Nuclear Magnetic Resonance Spectroscopy

[Chapter 12 - Week 12-13]
Alcohols and Ethers


[Chapter 13 - Week 14-15]
Aldehydes and Ketones

[Chapter 14 - Week 16]
Carboxylic acids and their derivatives

[Chapter 15 - Week 17]
Reactions and biological aspects of carboxylic acid Derivatives

[Chapter 16.1,16.2 - Week 18]
Enols and enolates

[Chapter 17.1-17.3 - Week 18]

[Chapter 19.1-19.4 - Week 19-20]
Aromatic Compounds

[Chapter 20.1-20.5 - Week 21]
Free Radicals

[Chapter 22 - Week 22]

[Chapter 25 - Week 23-24]

[Chapter 26 - Week 25]
Amino acids, peptides, and proteins

[Week 26]
Review (?)


Seyhan Ege: Organic Chemistry, Heath; 3rd Edition.

Other modern textbooks of organic chemistry may be used. For example:
R.J. Fessenden and J.S. Fessenden; Organic Chemistry, Wadsworth Publishers
T.W.G. Solomons; Fundamentals of Organic Chemistry, John Wiley and Sons
L.G. Wade Jr., Organic Chemistry, 2nd Edition.

Please note that references to book sections relevant to lecture material, problems etc. will be made to Ege 3rd Edition.

Molecular Models: Darling Models (preferred); Prentice Hall Models are acceptable.

Laboratory and Tutorial Scheduling

For 1997-98 each student registered in Chemistry 2O6 must attend one Laboratory period (3 hours) every two weeks and one Tutorial session (110 minutes) roughly once a month. A Demonstrator will be assigned to groups of 12-14 students, and a Tutorial Leader to groups of 55 to 65. Students will be assigned to either GROUP I or GROUP II on Thursday September 4th 1997. These will be posted in the 2O6 notice board on the second floor of BSB between labs 201 and 212. The method of conflict resolution will be announced in class on the same day. Please note that because of Thanksgiving, students in the Monday groups will have a slightly different schedule to the other groups in the First Term.

The Laboratory Manual is available online via the homepage. Students are responsible for printing out their own copies of the relevant material for each session in the laboratory.

Laboratory Notebook: Hardcover, 7" x 9" (or any other hardcover notebook)

Students should note that arbitrary switching between tutorial groups will not be permitted.


The final grade for the course will be determined on the basis of the following approximate weighting:

Tutorials 7%
Assignments 7%
Midterms 22%
Laboratories 14%
Final Exam 50%

In order to pass the course the laboratory work must be completed with a passing grade and: a passing grade must be attained in the final examination.

Failure to hand in an assignment, complete a laboratory experiment, or write a midterm test will result in a zero grade, unless a valid excuse has been filed with the Associate Dean's office.  It is the student's responsibility to ensure that medical slips, etc. are filed with the Dean

If a midterm is missed for valid reasons, the 11% will be transferred to the final examination.

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02sep97; wjl