I wonder if someone of you have experience with so called "interleaved"
acquisition (i.e. when the signals from two (or more) nuclei are acquired at
the same time) on AMX/DMX/DSX instruments.
I need to run a kinetics, but I'd like to acquire signals from 13C(or 31P)
and
1H at the same time (or shifted apart not more than a second or so).
Needless
to say that I can not use signals from two separate runs. The signals in
both
channel are sufficiently strong to be registered from a single scan, there
is
no need for decoupling and there are no complications from relaxation. But
it has to be done fast. It takes less than 50-100 seconds for reaction to
complete, so I need some fast way to switch acquisition channels during
the experiment.
One possible way I can think about, is to generate a bunch of data sets,
such
that the odd numbered ones have parameters for protons, and the even
numbered - for 13C. Then I need just to run an AU, say MULTIZG. This works,
but it takes quite a long time for computer to switch from one data set to
another, so delay between two consecutive scans is newer shorter than 5-6
seconds, which is way too long. Processing of such sets is not much fun
either.
Here is my question: Is any way to do this faster and in more efficient way?
Or maybe you already have a pulse/AU program you are willing to share?
Any suggestions are very welcome.
Thank you,
Igor
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Igor Moudrakovski
Research Officer
Steacie Institute for Molecular Sciences
National Research Council
Ottawa, K1A 0R6
Canada
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