Department Seminar, Dr. Youla S. Tsantrizos, McGill University, Wednesday, January 19, 1:30
Jan 19, 2023
1:30PM to 2:30PM
Date(s) - 19/01/2023
1:30 pm - 2:30 pm
Next week we will welcome Dr. Youla Tsantrizos of McGill University to deliver a virtual department seminar.
Title: Asymmetric Synthesis of Bioisosteres and their Applications in Drug Discovery
Date: Thursday, January 19, 2023
Zoom: please email email@example.com for Zoom details
Host: Hana Mirvakili
Abstract: The overall objective of our research is to exploit the molecular recognition elements affecting chemical and biological transformations. We are designing novel phosphorus-containing molecules that can be used as: (I) Leads in Medicinal Chemistry or as (II) Ligands in Metal-Mediated and Organocatalytic Asymmetric Synthesis.
There are obvious benefits to combining studies in novel synthetic methodologies with studies in medicinal chemistry and consequently, we aim to identify asymmetric catalytic reactions that can supported the efficient and safe synthesis of human therapeutics. Examples will be presented to illustrate the extensive “cross-pollination” between our efforts in asymmetric synthesis and medicinal chemistry projects focusing the treatment of various cancers, including hematological cancers, pancreatic ductal adenocarcinoma and colorectal cancer.