Research Interests: Radiochemistry, bioconjugate chemistry, organic synthesis, PET molecular imaging

Research focuses on: the design, synthesis and assessment of novel PET imaging radiopharmaceuticals.

I’m a new faculty member in the Dept. of Chemistry & Chemical Biology and a radiopharmaceutical chemist. My team and I will be designing and testing radioactive diagnostic probes (radiotracers) for in vivo molecular imaging applications, in particular positron emission tomography (PET) tracers.å

Areas of research will include:

• efficient and broadly-useful radiosynthetic techniques, in particular those related to the incorporation of 18F into bioactive small molecules;
• new bioconjugation strategies for the modification of potential peptide and protein-based targeting vectors, and;
• pathologies that currently lack clinically-relevent, ‘gold-standard’ molecular imaging agents (e.g. diabetes, bacterial infection).”
• Website: McMaster Radiochemistry and Radiopharmaceuticals

Website: McMaster Radiochemistry and Radiopharmaceuticals

Publications: See OrcID for a list of Dr. Inkster’s most recent publications

Dr. Jose Moran-Mirabal

Research focuses on:Inorganic fluorine chemistry, noble-gas chemistry, main-group and transition-metal chemistry, radiochemistry

http://unicorn.mcmaster.ca/

Research focuses on: Pedagogy in Chemistry and Chemical Biology

• Exploring the use of social media to enhance student learning and engagement in large introductory classes
• Development of modern and innovative chemical biology laboratory experiences to enhance student learning
• Development of OER resources in Chemistry and Chemical Biology

Research focuses on: Chemical education and pedagogy: creating, applying, and evaluating new technologies and assessment methods in the chemistry curriculum

Our research program aims to use novel methods to understand how chemical exposure and other environmental factors influence human and ecosystem health. Our areas of investigation include:

1. Development of novel analytical methods and physical and chemical databases
2. Design and development of novel passive sampling and modelling methods
3. Application of novel methods and databases in human and ecosystem studies

Research focuses on:Micro- and nanostructured materials fabrication and applications; nanocellulose surface chemistry; 3D printing; biosensors; super-resolution fluorescence microscopy, biomolecular interactions

Dr. Styler leads the P.A.R.T.I.C.L.E.S. (pesticides, art, road dust, traffic, interdisciplinary, combustion, light, equity, surfaces) research group, which currently consists of five excellent graduate students, one stellar undergraduate trainee, and one fantastic postdoctoral researcher.

As our name suggests, we are interested in a wide range of environmentally related topics:

• chemistry on atmospheric surfaces, including desert/urban dust, wildfire particulate matter, urban surfaces, and cultural heritage objects;
• air quality, climate, and health impacts of atmospheric processes;
• pollutant transformations in complex environmental matrices;
• interdisciplinary engagement (e.g., high-throughput reactor design, art conservation science);
• environmental justice (e.g., collaboration with community partners to identify disparities in pollutant exposure)

We are always looking for enthusiastic undergraduate and graduate students to join our team. As of Spring 2022, please contact us through the standardized form on the P.A.R.T.I.C.L.E.S. website if you are interested in finding out more about the work we do and how it might fit with your own interests and goals.

Research focuses on:DNA Nanotechnology, Supramolecular DNA Assembly, Spherical Nucleic Acids, Chemical Biology

Research focuses on:Organometallic and Coordination Chemistry, Molecular Inorganic Synthesis, Ligand Design, Reactivity Studies and Catalysis, Atomic Layer Deposition

Research focuses on: Thermoelectric materials; inorganic phosphors for temperature sensing

Research focuses on:Supramolecular Main-Group Chemistry: New Materials and Functional Multimolecular Assemblies

Research focuses on:Magnetic Resonance Spectroscopy and Imaging of Materials for Alternative Energy Storage & Conversion; Lithium Ion Batteries & Fuel Cells

Our research group aims to apply advanced solid-state nuclear magnetic techniques, in combination with electrochemical characterisation, to the study of materials of interest as chemical power sources. Lithium ion batteries and proton exchange membrane fuel cells (PEM-FC) provide environmentally friendly energy alternatives. Emerging technologiesinclude sodium ion batteries, and sodium/lithium-air batteries, which are exciting, but so far poorlyunderstood & controlled. Solid-state NMR is well known for its ability to provide site-specific information on structure and dynamics. Weutilise multi-nuclear approaches including 7Li, 6Li, 23Na, and 1H, to investigate processes and interactions such as electrochemical transport, ionic conductivity,hydrogen-bonding,and polymer chain ordering or mobility. In recent years, the field of magnetic resonance has experienced rapid technological and methodological growth, allowing a broader range of materials questions to be addressed.

Research focuses on: Bioanalytical chemistry; metabolomics; exposomics; biomarker discovery; clinical biochemistry; capillary electrophoresis; mass spectrometry; chemometrics; bimolecular interactions; drug screening; newborn screening; population health; nutrition; precision health

Research focuses on: Pre-clinical molecular pharmacology of neurodegenerative diseases and cancer; intrinsically unstructured amyloidogenic proteins: protein kinases & signaling; functional protein dynamics and allosteric regulation; Nuclear Magnetic Resonance (NMR)

Research focuses on: Transition-state analysis, enzyme inhibition, inhibitor design, enzyme mechanisms

Research focuses on: Delivery vehicles, controlled release, immunotherapeutics, immune-directing polymer coatings

The Wylie Lab develops protein-polymer conjugates for:
1. Delivery of biologics, primarily polymer-antibody conjugates, for applications in cancer immunotherapy and degenerative retinal diseases
2. Bioreactors to modulate blood chemistry towards the treatment of sepsis
3. Bio-inks for the 3D printing of tissues to improve drug screening efficiency

Please visit wylielab.com for more information.

Research focuses on: Surfaces, interface and low-dimensional materials; their electronic and chemical properties; doping, mobility and pattern formation; applications in corrosion inhibitors and water quality sensors

Research focuses on:Sol-gel chemistry; self-assembly; photonics and photo-induced transformations

Research focuses on: Organic Synthesis; Medicinal Chemistry; Natural Products; Organocatalysis; Transition-metal Catalysis;Total Synthesis

Research focuses on:Polymer Chemistry of Nanotubes; Dendrimer-Based Therapeutics; Covalent Functionalization of Single-Walled Carbon Nanotubes (SWNTs); SupramolecularFunctionalization of SWNTs; Dendrimer-Based Imaging Agents

Current research projects can be separated into two main areas, including the polymer chemistry of carbon nanotubes, and dendrimer-based therapeutics. In the former, both covalent and non-covalent carbon nanotube functionalization strategies are being explored, with a focus on producing functional materials that combine the properties of carbon nanotubes with those of other nano-scale structures. In the area of dendrimer-based therapeutics, the emphasis is on the development and investigation of simultaneous diagnostic imaging and drug delivery agents.

Research focuses on:Synthesis to make silicones more sustainable: controlling biological and interfacial properties by incorporating natural materials, new routes to recycle automotive tires, development of strategies to create precise silicones with precise properties

Research focuses on:Relativistic quantum dynamics; quantum and semiclassical molecular dynamics; simulation of NMR spectra

Research focuses on:

• Differentiable programming for computational chemistry
• Machine learning for physical sciences
• Inverse molecular design

In-silico simulations of molecular systems are challening and it requires great computational resources to simulate real-size systems like chemical reactions, proton, and energy transfer in molecular aggregates, to mention a few. Therefore, there is a need to incorporate and develop numerical tools that scale for real-size simulations of molecular systems. My research group’s primary focus is on developing new numerical methodologies based on machine learning algorithms and modern tools to tack real-size quantum systems.

Research focuses on: Mathematical methods, conceptual tools, and computational software for molecular modelling; New electronic structure theory methods; Concepts in quantum chemistry; Machine learning for chemical property prediction

Research focuses on: Molecular imaging, radiolabeling methodologies, targeted radiotherapeutics, preclinical in vitro and in vivo validation of radiopharmaceuticals, clinical translation

Dr. Peter Kruse

Dr. Paul Ayers

Dr. Joseph Okeme

Dr. Maikel Rheinstädter

Dr. Saman Sadeghi

Dr. Jakob Magolan

Dr. James McNulty

Dr. Sarah Styler

Dr. Ryan Wylie

Dr. Sarah Styler

Dr. Paul W. Ayers

Dr. Ignacio Vargas-Baca

Dr. Gillian Goward

Dr. Ryan Wylie

Dr. Peter Kruse

Dr. Katherine Bujold

Dr. Giuseppe Melacini

Dr. Alex Adronov

Dr. Sam Sadeghi

Dr. Adam Hitchcock

Dr. Ryan Wylie

Dr. Saman Sadeghi

Dr. Philip Britz-McKibbin

Dr. John Whitney

Dr. Jose Moran Mirabal

Dr. Jose Moran-Mirabal

Dr. David Emslie

Dr. Sarah Styler

Dr. Katherine Bujold

Dr. Philip Britz-McKibbin

Dr. David Emslie

Dr. Alex Adronov

Dr. Giuseppe Melacini

Dr. Anthony Rullo

Dr. Yurij Mozharivskyj

Dr. Giuseppe Melacini

Dr. Peter Kruse

Dr. Anthony Rullo

Dr. Michael Brook

Dr. Jakob Magolan

Dr. Yingfu Li

Dr. Jakob Magolan

Dr. Giuseppe Melacini

Dr. Ignacio Vargas-Baca

Dr. Kalai Saravanamuttu

Dr. Sarah Styler

Dr. Kalaichelvi Saravanamuttu

Dr. Saman Sadeghi

Dr. Giuseppe Melacini

Dr. Sarah Styler

Dr. Sarah Styler

Dr. Peter Kruse

Dr. Paul Ayers

Dr. Paul Berti

Dr. Michael Brook

Dr. David Emslie

Dr. Sam Sadeghi

Dr. Gillian Goward

Dr. Yurij Mozharivskyj

Dr. Philip Britz-McKibbin

Dr. Ryan Wylie

Drs. Katherine Bujold and Yingfu Li

Dr. Alex Adronov

Dr. Jakob Magolan

Dr. Paul Ayers

Drs. Rullo/Bramson

Dr. Mike Brook

Dr. Harald Stover

Dr. Kalai Saravanamuttu

Drs. Anthony Rullo and Jonathan Bramson

Dr. Kalai Saravanamuttu

Dr. James McNulty

Dr. Jose Moran Mirabal

Dr. John Valliant

Dr. Harald Stover

Dr. Kalai Srarvanamuttu

Dr. Saman Sadeghi

Dr. Ryan Wylie

Dr. Saman Sadeghi

Dr. Greg Slater

Dr. Jakob Magolan

Dr. John Valliant

Dr. Sarah Styler

Dr. Anthony Rullo

Dr. Sarah Styler

Dr. Alex Adronov

Dr. Gillian Goward

Dr. Katherine Bujold

Dr. David Emslie

Dr. Mike Brook

Drs. Drew Higgins and Adam Hitchcock

Dr. James McNulty

Research interests include medicinal inorganic and radiopharmaceutical chemistry.
Dr. John Valliant

Dr. Saman Sadeghi

Dr. Ayman A. Ibrahim is a visiting postdoctoral scholar at McMaster University under the supervision of Dr. Saman Sadeghi. Ayman finished his Ph.D in Pharmacology & Toxicology at Faculty of Pharmacy, Cairo University, Egypt (2019). He also received his master’s degree in 2016 from Zagazig University, Egypt. Noteworthy, he has a strong experience in Quality control, Quality assurance, GMP and production of 99Mo/99mTc, 131I, 125I & 51Cr radiopharmaceuticals. Generally, his main scientific interests are pharmacodynamics and pharmacokinetics of novel radiopharmaceuticals used in diagnosis and therapy & development of new treatment strategies against multiple diseases induced by ionizing radiation.
Dr. Saman Sadeghi

Dr. Mike Brook

Dr. Gary Schrobilgen

Dr. David Emslie

Dr. Gillian Goward

Dr. Gillian Goward

Dr. Phil Britz McKibbin

Dr. Saman Sadeghi

Dr. James McNulty

Dr. Giuseppe Melacini

Supervisor: Dr. Rodrigo Vargas-Hernandez