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Chemical Biology

Chemical Biology Is The Application Of Chemistry To Solve Biological Problems.

Chemical Biology at McMaster applies chemical techniques and tools to study and manipulate of biological systems. This includes studying interactions between small molecules and macromolecules (proteins and nucleic acids), and molecules of all sizes (polymers) with biological systems, including cells and whole organisms. Much of this work involves preparing, characterizing and delivering compounds (from small molecules all the way to antibodies) that might be used as drugs or diagnostics. We synthesize new complexing agents to deliver transition metals to specific organs in the body for use in radio-imaging such as MRI, PET scans, and other medical applications. We also develop analytical techniques for metabolomics research, and biosensors to rapidly diagnose infections.

Areas of specialty include:

  • In vivo delivery
  • Drug and metabolite detection
  • Bioimaging
  • Biosensors

Our Researchers:

Paul Berti

Professor, Associate Chair (Undergraduate Studies)

John Brennan

Professor, Canada Research Chair in Point-of-Care Diagnostics

Yingfu Li

Professor, Departments of Biochemistry & Biomedical Sciences and Chemistry & Chemical Biology

Nathan Magarvey

Associate Professor, Departments of Biochemistry & Biomedical Sciences and Chemistry & Chemical Biology

A portrait of Jakob Magolan.

Jakob Magolan

Associate Professor, Department of Biochemistry & Biomedical Sciences

A portrait of Anthony Rullo.

Anthony Rullo

Associate Professor, Department of Medicine

Ryan Wylie

Associate Professor, Acting Director of Chemical Biology (Graduate Studies)